Search Results - diagnostics

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Autoregulation of the Na+, K+-ATPase by the C-terminus

Drug screening platform based on the crystal structure of certain ion pumps The present invention relates the groundbreaking discovery of the crystal structure of certain ion pumps recently published in Nature. The exchange of signals and matter between a cell and its surroundings is ensured by ion pumps and receptors embedded in the cell...

Published: 9/12/2025 | Updated: 4/20/2016 | Inventor(s): Poul Nissen, Jens Preben Morth, Bente Vilsen, Jens Peter Andersen

Keywords(s): Diagnostics, Therapeutics, White Biotech, z_DoNotUse_Pharma

Category(s): Life Sciences and Medical Devices

Methylation biomarkers for prostate cancer

Novel diagnostic and prognostic markers for prostate cancer using methylated DNA. Technical Field Biotech, Pharma Business opportunity Research collaboration to validate the technology Current state of technology Methylation-sensitive qPCR (MS-qPCR) assays have been developed and tested in ~500 clinical samples from prostate...

Published: 9/12/2025 | Updated: 12/5/2012 | Inventor(s): Karina Dalsgaard Sørensen, Christa Haldrup, Torben Falck Ørntoft

Keywords(s): Diagnostics, White Biotech, z_DoNotUse_PrognosisScreening

Category(s): Life Sciences and Medical Devices

Novel binding pocket for Sodium, Potassium regulation - A drugable target with new opportunities

References [1] Morth JP, Pedersen BP, Toustrup-Jensen MS, Sørensen TL, Petersen J, Andersen JP, Vilsen B, Nissen P (2007). Crystal structure of the sodium-potassium pump. Nature 450, 1043-1049; and: Nyblom M, Reinhard L, Poulsen H, Andersson M, White S, Gourdon P, Vilsen B, Nissen P (2012). Crystal structure of the sodium...

Published: 9/12/2025 | Updated: 11/2/2012 | Inventor(s): Poul Nissen, Jens Preben Morth, Bente Vilsen, Jens Peter Andersen

Keywords(s): Diagnostics, Therapeutics, White Biotech, z_DoNotUse_Pharma

Category(s): Life Sciences and Medical Devices

Perfusion Measurement

The group has discovered that oxygen availability in tissue depends critically on capillary transit time heterogeneity (CTTH), and not, as hitherto believed, only on local blood supply and blood oxygenation. This is a fundamentally new insight and research breakthrough. As a result, altered capillary morphology in ageing and disease can cause...

Published: 9/12/2025 | Updated: 7/24/2012 | Inventor(s): Leif Østergaard, Sune N Jespersen, Kim Beaushau Mouridsen, Martin Snejbjerg Jensen, Kartheeban Nagenthiraja, Anna Tietze

Keywords(s): Diagnostics, Digital, MedTech, z_DoNotUse_Digital, z_DoNotUse_MedicalImaging, z_DoNotUse_PrognosisScreening

Category(s): Life Sciences and Medical Devices